Chrona Commons · public archive
Small biotech
deserves to win.
Chrona Commons is a public archive of complete Investigational New Drug applications — donated by biotechs, sponsored by 1Day Sooner, stewarded by Renaissance Philanthropy, made readable for the next generation of regulatory professionals.
Have a Commons account? Sign inSponsored by 1Day Sooner · stewarded with Renaissance Philanthropy
— Why Commons exists
The big‑pharma advantage isn't science — it's institutional infrastructure. Access to complete submission histories, to how FDA questions get answered, to what a well‑constructed IND actually looks like. Commons exists to close that gap.
Chrona reads · humans write
03 — Approved vs. how it got approved
Drugs@FDA shows what got approved.
Commons shows how.
Public archives show endpoints — the approval letter, the label, the redacted summary. They tell you what the answer was. Commons is the process record — every sequence, every amendment, every FDA question and every sponsor response.
It tells you how the answer was reached, what went wrong along the way, and what a well‑constructed regulatory argument looks like under pressure.
04 — What's in the archive
Real, complete INDs.
Every sequence. Every amendment. FDA correspondence and sponsor responses. The full longitudinal record of how a regulatory conversation unfolds — not just what got approved. All PII redacted before donation.
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Every sequence
From original submission through final amendment.
The eCTD lifecycle, complete. Initial INDs, safety reports, protocol amendments, manufacturing changes — in order, with the sponsor's own metadata.
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FDA correspondence
Information Requests, clinical hold letters, sponsor responses.
Both sides of the conversation. The questions reviewers asked, the answers the sponsor wrote, and the timing between them.
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Full text search
Read, search, and download. Free account to view.
Look up an §3.2.P.2 across the archive. Pull every dose-finding rationale ever donated. A research surface, not a portal.
1Day Sooner Renaissance Philanthropy Chrona Bio
Built with 1Day Sooner and Renaissance Philanthropy.
Renaissance Philanthropy acquires complete IND portfolios from biotechs that have shut down or shelved programs. These are full records — not redacted summaries, not FOIA fragments. Chrona Bio is the technology partner: we built the archive, the search infrastructure, and the viewer.
1Day Sooner sponsors Commons. Its support is what keeps the archive free and public, and it helps administer the Commons community around it.
This is an institutional partnership, not a vendor relationship. 1Day Sooner sponsors the mission. Renaissance Philanthropy stewards the donor pipeline. Chrona Bio makes the records accessible. The public gets the data.
Sponsorship
1Day Sooner mission support · community
Stewardship
Renaissance Philanthropy donor pipeline · acquisition · custodianship
Technology
Chrona Bio archive · search · viewer · redaction
06 — For Chrona Bio users
How Commons connects to Chrona Bio.
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Free · sign up to read
Explore on your own
Create an account and read complete INDs — the same document types you work with, from biotechs that faced the same challenges yours does. No sales call.
Explore the archive -
For your team
Bring it to your team
Commons gives you the Viewer — read complete reference INDs. Chrona Bio Enterprise brings that same viewer to your own submissions, plus cross-document findings and section-state tracking across your team's INDs.